[Sarah M.]

Okay I promised I’d report back and here I am! Started GHK-Cu 6 weeks ago after getting advice in the Getting Started channel.

What I used: topical serum applied AM and PM to face and neck.

Weeks 1-2: Nothing dramatic. Skin felt a tiny bit more plump maybe? Hard to tell if I was imagining it.

Weeks 3-4: Okay this is when I started to really notice. The texture on my forehead (I have some mild crepiness from sun exposure) feels noticeably smoother. The fine lines around my eyes look softer in morning light.

Weeks 5-6: The collagen density feel is real, my skin has more of that firm-but-bouncy quality I remember from my late 20s. A friend who didn’t know I was doing anything commented that my skin looked “glowy.” That was the confirmation I needed

I’m going to continue and will do a 12-week update. Also considering adding PTD-DBM for my hairline at the temples, has anyone used both together?

[Pete C.]

Love this write-up Sarah! The timeline you’re describing is consistent with what the collagen synthesis research suggests. GHK-Cu upregulates collagen and glycosaminoglycan production, but connective tissue changes take weeks to accumulate.

On PTD-DBM: yes, it can be combined with GHK-Cu and there’s some logic to it, they work on different pathways (GHK-Cu on collagen/wound healing, PTD-DBM on Wnt signaling for follicle regeneration). Some people alternate AM/PM, some use GHK-Cu for skin and PTD-DBM specifically on the hairline. I’d start them separately so you can attribute any changes accurately.

[Mia T.]

The ‘glowy’ comment from a friend is the real validation Those unsolicited compliments hit different.

I’ve been on GHK-Cu for about 4 months now and the effects have continued to build past the 6-week mark, so definitely stick with it. My skin just looks healthier overall.

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